Allison E. Ashley-Koch

Professor in Medicine, Faculty Fellow of the Center for Child and Family Policy

One of my major research foci is in the genetic basis of psychiatric and neurological disorders. I am currently involved in studies to dissect the genetic etiology of attention deficit hyperactivity disorder (ADHD), autism, chiari type I malformations, essential tremor, and neural tube defects. Additional research foci include genetic modifiers of sickle cell disease, and genetic contributions to birth outcomes, particularly among African American women.

Research Interests:

  • ADHD


  • Ph.D. Emory University - 1997

Recent Publications (More Publications)

  • WD Taylor, DC Steffens, A Ashley-Koch, ME Payne, JR MacFall, CF Potocky, KR Krishnan (2010) Angiotensin receptor gene polymorphisms and 2-year change in hyperintense lesion volume in men. Molecular psychiatry, 15, 816-22, [doi], [abs]
  • CA Markunas, KS Quinn, AL Collins, ME Garrett, AM Lachiewicz, JL Sommer, E Morrissey-Kane, SH Kollins, AD Anastopoulos, AE Ashley-Koch (2010) Genetic variants in SLC9A9 are associated with measures of attention-deficit/hyperactivity disorder symptoms in families. Psychiatric genetics, 20, 73-81, [doi], [abs]
  • P Sebastiani, N Solovieff, SW Hartley, JN Milton, A Riva, DA Dworkis, E Melista, ES Klings, ME Garrett, MJ Telen, A Ashley-Koch, CT Baldwin, MH Steinberg (2010) Genetic modifiers of the severity of sickle cell anemia identified through a genome-wide association study. American journal of hematology, 85, 29-35, [doi], [abs]
  • SH Kollins, ME Garrett, FJ McClernon, AM Lachiewicz, E Morrissey-Kane, D FitzGerald, AL Collins, AD Anastopoulos, AE Ashley-Koch (2009) Effects of postnatal parental smoking on parent and teacher ratings of ADHD and oppositional symptoms. The Journal of nervous and mental disease, 197, 442-9, [doi], [abs]
  • S Z├╝chner, JR Wendland, AE Ashley-Koch, AL Collins, KN Tran-Viet, K Quinn, KC Timpano, ML Cuccaro, MA Pericak-Vance, DC Steffens, KR Krishnan, G Feng, DL Murphy (2009) Multiple rare SAPAP3 missense variants in trichotillomania and OCD. Molecular psychiatry, 14, 6-9, [doi]
  • KL Deak, DG Siegel, TM George, S Gregory, A Ashley-Koch, MC Speer, NTD Collaborative Group (2008) Further evidence for a maternal genetic effect and a sex-influenced effect contributing to risk for human neural tube defects. Birth defects research. Part A, Clinical and molecular teratology, 82, 662-9, [doi], [abs]
  • AE Ashley-Koch, L Elliott, ME Kail, LM De Castro, J Jonassaint, TL Jackson, J Price, KI Ataga, MC Levesque, JB Weinberg, EP Orringer, A Collins, JM Vance, MJ Telen (2008) Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease. Blood, 111, 5721-6, [doi], [abs]
  • AE Ashley-Koch, J Jaworski, de Q Ma, H Mei, MD Ritchie, DA Skaar, G Robert Delong, G Worley, RK Abramson, HH Wright, ML Cuccaro, JR Gilbert, ER Martin, MA Pericak-Vance (2007) Investigation of potential gene-gene interactions between APOE and RELN contributing to autism risk. Psychiatric genetics, 17, 221-6, [doi], [abs]
  • S Zuchner, ML Cuccaro, KN Tran-Viet, H Cope, RR Krishnan, MA Pericak-Vance, HH Wright, A Ashley-Koch (2006) SLITRK1 mutations in trichotillomania. Molecular psychiatry, 11, 887-9, [doi]
  • AE Ashley-Koch, H Mei, J Jaworski, DQ Ma, MD Ritchie, MM Menold, GR Delong, RK Abramson, HH Wright, JP Hussman, ML Cuccaro, JR Gilbert, ER Martin, MA Pericak-Vance (2006) An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA receptor subunit genes on 15q11-q13 as risk factors for autistic disorder. Annals of human genetics, England, 70, 281-92, , [abs]
  • E Reid, M Kloos, A Ashley-Koch, L Hughes, S Bevan, IK Svenson, FL Graham, PC Gaskell, A Dearlove, MA Pericak-Vance, DC Rubinsztein, DA Marchuk (2002) A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10). American journal of human genetics, United States, 71, 1189-94, , [abs]
  • A Ashley-Koch, ER Bonner, PC Gaskell, SG West, R Tim, CM Wolpert, R Jones, CD Farrell, M Nance, IK Svenson, DA Marchuk, RM Boustany, JM Vance, WK Scott, MA Pericak-Vance (2001) Fine mapping and genetic heterogeneity in the pure form of autosomal dominant familial spastic paraplegia. Neurogenetics, England, 3, 91-7, , [abs]
  • A Ashley-Koch, CM Wolpert, MM Menold, L Zaeem, S Basu, SL Donnelly, SA Ravan, CM Powell, MB Qumsiyeh, AS Aylsworth, JM Vance, JR Gilbert, HH Wright, RK Abramson, GR DeLong, ML Cuccaro, MA Pericak-Vance (1999) Genetic studies of autistic disorder and chromosome 7. Genomics, UNITED STATES, 61, 227-36, , [abs]
  • AE Ashley-Koch, H Robinson, AE Glicksman, SL Nolin, CE Schwartz, WT Brown, G Turner, SL Sherman (1998) Examination of factors associated with instability of the FMR1 CGG repeat. American journal of human genetics, UNITED STATES, 63, 776-85, , [abs]